Following a decade long study, scientists at the Buck Institute and the University of Washington have identified 238 genes linked to aging, that, when removed, increased the lifespan of cultured S. cerevisiae yeast cells. These results provide new geonomic targets that could eventually be used to improve human health. Brian Kennedy, Buck Institute CEO, and lead author of the published research, explains, “This study looks at aging in the context of the whole genome and gives us a more complete picture of what aging is. It also sets up a framework to define the entire network that influences aging in this organism.”
This research is part of a larger process to map the relationships between all the gene pathways that govern aging, illuminating this critical process in yeast, worms and mammals. The researchers hope that, ultimately, these efforts will produce new therapies. For more information, visit the Buck Institute website.